See all publications on PubMed
Publications
Zhang Y*$, Yeganeh PN*, Zhang H, Wang SY, Li Z, Gu B, Lee DJ, Zhang Z, Ploumakis A, Shi M, Wu H, Greer EL, Hide W$, and Lieberman J$, Tumor editing suppresses innate and adaptive antitumor immunity and is reversed by inhibiting DNA methylation Nat Immunol doi:10.1038/s41590-024-01932-8 (2024) * co-first authors $ co-corresponding authors Read on PubMed | PDF
Rothi MH, Sarkar GC, Al Haddad J, Mitchell W, Ying K, Pohl N, Sotomayor-Mena RG, Natale J, Dellacono S, Gladyshev VN, and Greer EL, The 18S rRNA Methyltransferase DIMT-1 Regulates Lifespan in the Germline Later in Life bioRxiv doi: https://doi.org/10.1101/2024.05.14.594211 (2024) Read on PubMed | PDF
Liberman N, Rothi MH, Gerashchenko M, Zorbas C, Boulias K, MacWhinnie FG, Ying AK, Taylor AF, Al Haddad J, Shibuya H, Roach L, Dong A, Dellacona S, Lafontaine DLJ, Gladyshev VN, and Greer EL, 18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesis Molecular Cell 83: 1-15 (2023) Read on PubMed | PDF
Takashima K, Lee DJ, Trovero MF, Rothi MH, MIstry M, Zhang Y, Li Z, Davis CP, Li Z, Natale J, Schmid E, Al Haddad J, Hoffmann GB, Dietmann S, Sui SH, Oshiumi H, Lieberman J, and Greer EL, NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression, bioRxiv doi: https://doi.org/10.1101/2023.06.13.544862 (2023) Read on PubMed | PDF
Pollina EA and Greer EL, Prometheus unshackled: Liver regeneration makes you young, Mol Cell May 18;83(10):1546-1548. doi: 10.1016/j.molcel.2023.04.024. (2023) (Preview) Read on PubMed | PDF
Sarkar G and Greer EL, Inheritance of directed DNA cytosine methylation in mammals, Lab Anim May;52(5):105-107. doi: 10.1038/s41684-023-01158-5. (2023) (News & views) Read on PubMed | PDF
Jimenez NA, Castellano M, Santillan EM, Boulias K, Boan A, Padilla LFA, Fernandino JI, Greer EL, Tosar JP, Cochella L, and Strobl-Mazzula PH, Paternal methotrexate exposure affects sperm small RNA content and causes craniofacial defects in the offspring, Nat Commun Mar 23;14(1):1617. doi: 10.1038/s41467-023-37427-7. (2023) Read on PubMed | PDF
Greer EL, Deadly males accelerate aging with piRNAs, Nat Aging Jan;3(1):7-8. doi: 10.1038/s43587-022-00347-0. (2023) (News & views) Read on PubMed | PDF
Wang SY, Kim K, O'Brown ZK, Levan A, Dodson AE, Kennedy SG, Chernoff C, and Greer EL, Hypoxia induces transgenerational epigenetic inheritance of small RNAs, Cell Rep Dec 13;41(11):111800. doi: 10.1016/j.celrep.2022.111800 (2022) Read on PubMed | PDF
O'Brown ZK and Greer EL, N6-methyladenine: A Rare and Dynamic DNA Mark Adv Exp Med Biol 1389:177-210 (2022) (book chapter) Read on PubMed | PDF
Rothi MH and Greer EL, From correlation to causation: The new frontier of transgenerational epigenetic inheritance Bioessays Nov 9;e2200118. doi:10.1002/bies/202200118 (2022) (review) Read on PubMed | PDF
Boulias K and Greer EL, Biological roles of adenine methylation in RNA Nat Rev Genet Oct 19. doi: 10.1038/s41576-022-00534-0 (2022). Read on PubMed | PDF
Barna M, Karbstein K, Tollervey D, Ruggero D, Brar G, Greer EL, and Dinman JD, The promises and pitfalls of specialized ribosomes Mol Cell Jun 16;82(12):2179-2184 (2022) (voices) Read on PubMed | PDF
Boulias K and Greer EL, Means, mechanisms and consequences of adenine methylation in DNA Nat Rev Genet Jul;23(7):411-428. doi: 10.1038/s41576-022-00456-x (2022) Read on PubMed | PDF
Boulias K and Greer EL, The adenine methylation debate Science 375(6580):494-495 (2022) (perspective) Read on PubMed | PDF
Burton NO and Greer EL, Multigenerational epigenetic inheritance: Transmitting information across generations, Semin Cell Dev Biol Aug 20;S1084-9521(21)00210-X doi: 10.1016/j.semcdb.2021.08.006 (2021) Read on PubMed | PDF
Tartell MA, Boulias K, Hoffmann GB, Bloyet LM, Greer EL$, and Whelan SPJ$, Methylation of viral mRNA cap structures by PCIF1 attenuates the antiviral activity of interferon-β, PNAS 118(29) e2025769118; https://doi.org/10.1073/pnas.2025769118 (2021) $ co-corresponding authors Read on PubMed | PDF
Coe A, Biller SJ, Thomas E, Boulias K, Bliem C, Arellano A, Dooley K, Rasmussen AN, LeGault K, O'Keefe TJ, Greer EL, and Chisholm SW, Coping with darkness: The adaptive response of marine picocyanobacteria to repeated light energy deprivation Limnology and Oceanography 66(7): https://doi.org/10/1002/lno.11880 (2021) Read on PubMed | PDF
Wang SY, Pollina EA, Wang IH, Pino LK, Bushnell HL, Takashima K, Fritsche C, Sabin G, Garcia BA, Greer PL, and Greer EL, Role of Epigenetics in Unicellular to Multicellular Transition in Dictyostelium Genome Biology 22(1):134 https://doi.org/10.1186/s13059-021-02360-9 (2021) Read on PubMed | PDF
Boulias K and Greer EL, Detection of DNA Methylation in Genomic DNA by UHPLC-MS/MS, Methods Mol Biol 2198:79-90 (2021) Read on PubMed | PDF
Lieberman N*, O'Brown ZK*, Earl AS*, Boulias K, Gerashchenko MV, Wang SY, Fritsche C, Fady PE, Dong A, Gladyshev VN, and Greer EL, N6-adenosine methylation of ribosomal RNA affects lipid oxidation and stress resistance Science Advances 6(17): 1-14 eaaz4370 (2020) * co-first authors Read on PubMed | PDF
Lizarraga A, O'Brown ZK, Boulias K, Roach L, Greer EL, Johnson PJ, Strobl-Mazzulla PH, and de Miguel N, Adenine DNA methylation, 3D genome organization, and gene expression in the parasite Trichomonas vaginalis PNAS 27:201917286. doi: 10.1073/pnas.1917286117 (2020) Read on PubMed | PDF
Liberman N*, Wang SY*, and Greer EL, Transgenerational epigenetic inheritance: from phenomena to molecular mechanisms Curr Opin Neurobiol 59:189-206 (2019) (review) * co-first authors Read on PubMed | PDF
Wang SY*, Mao H*, Shibuya H*, Uzawa S, O’Brown ZK, Wesenberg S, Shin N, Saito TT, Gao J, Meyer BJ, Colaiacovo MP, and Greer EL, The Demethylase NMAD-1 Regulates DNA Replication and Repair in the Caenorhabditis elegans Germline PLoS Genetics 15(7):e1008252 (2019) * co-first authors Read on PubMed | PDF
Boulias K*, Toczydlowska-Socha D*, Halwey BR*, Liberman N, Takashima K, Zaccara S, Guez T, Vasseur JJ, Debart F, Aravind L, Jaffrey SR$, and Greer EL$, Identification of the m6Am methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome, Molecular Cell 75:1-13 (2019) * co-first authors $ co-corresponding authors Read on PubMed | PDF
Boulias K and Greer EL, Put the Pedal to the METTL1: Adding Internal m7G Increases mRNA Translation Efficiency and Augments miRNA Processing, Molecular Cell 74(6):1105-7 (2019)(preview) Read on PubMed | PDF
O'Brown ZK, Boulias K, Wang J, Wang SY, O'Brown NM, Hao Z, Shibuya H, Fady PE, Shi Y, He C, Megason SG, Liu T, and Greer EL, Sources of artifact in measurements of 6mA and 4mC abundance in eukaryotic genomic DNA, BMC Genomics 20(1):445 (2019) Read on PubMed | PDF
O'Brown ZK and Greer EL, N6-Methyladenine: A Conserved and Dynamic DNA Mark, Adv Exp Med Biol 945:213-246 (2016) (book chapter) Read on PubMed | PDF
Boulias K, Lieberman J, Greer EL, An Epigenetic Clock Measures Accelerated Aging in Treated HIV Infection Molecular Cell 62(2):153-5 (2016) (preview) Read on PubMed | PDF
Greer EL$, Becker B, Latza C, Antebi A, and Shi Y$, Mutation of C. elegans demethylase spr-5 extends transgenerational longevity Cell Research 26(2):229-38 (2016) $ co-corresponding authors Read on PubMed | PDF
Greer EL*$, Blanco MA*, Gu L, Sendinc E, Liu J, Aristizábal-Corrales D, Hsu C-H, Aravind L., He C, and Shi Y$ DNA methylation on N6-adenine in C. elegans Cell 161(4):868-78 (2015) (Cover Article) * co-first author $ co-corresponding authors Read on PubMed | PDF
Luo GZ, Blanco MA, Greer EL, He C$ and Shi Y$ DNA N6-methyladenine: a new epigenetic mark in eukaryotes? Nat Rev Mol Cell Biol. 16(12):705-10 (2015) (review) $ co-corresponding authors Read on PubMed | PDF
Selected Publications before 2015:
Greer EL, Beese-Sims SE, Brookes E, Spadafora R, Zhu Y, Rothbart SB, Aristizábal-Corrales D, Chen S, Badeaux AI, Jin Q, Wang W, Strahl BD, Colaiacovo MP, and Shi Y, A histone methylation network regulates transgenerational epigenetic memory in C. elegans, Cell Reports 7(1):113-26 (2014) Read on PubMed | PDF
Greer EL and Shi Y, Histone methylation: a dynamic mark in health, disease, and inheritance Nat Rev Genet 13(5):343-57 (2012) Read on PubMed | PDF
Greer EL, Maures TJ, Ucar D, Hauswirth AG, Mancini E, Lim JP, Benayoun BA, Shi Y, and Brunet A. Transgenerational Epigenetic Inheritance of Longevity in C. elegans, Nature (Article) 479(7373):365-71 (2011) Read on PubMed | PDF
Greer EL, Maures TJ, Hauswirth AG, Green EM, Leeman DS, Maro GS, Han S, Banko MR, Gozani O, and Brunet A. Members of the H3K4 Trimethylation Complex Regulate Lifespan in a Germline-dependent Manner in C. elegans. Nature 466(7304):383-7 (2010) Read on PubMed | PDF
Greer EL and Brunet A, Different Dietary Restriction Regimens Extend Lifespan by both Independent and Overlapping Genetic Pathways in C. elegans, Aging Cell 8(2):113-27 (2009) Read on PubMed | PDF
Greer EL, Dowlatshahi D, Banko MR, Villen J, Hoang K, Blanchard D, Gygi SP, and Brunet A, An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans, Curr Biol 17(19):1645-56 (2007) Read on PubMed | PDF
Greer EL, Oskoui PR, Banko MR, Maniar JM, Gygi MP, Gygi SP, and Brunet A, The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor, J Biol Chem 282(41):30107-19 (2007) Read on PubMed | PDF
